Phase Separation in Living Cells - Benefits and Risks

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Phase Separation in Living Cells: Benefits and Risks



https://CourseWikia.com

English | 2023 | ISBN: 9819948851 | 571 Pages | PDF EPUB (True) | 48 MB

Phase separation is a physico-chemical process that induces a single solution of solvent and intrinsically disordered proteins (IDPs) to separate into two phases, one phase containing only solvent and the other containing IDPs in the solvent. A key molecule in phase separation is the intrinsically disordered region (IDR) proteins (IDPs), mostly comprised of RNA-binding proteins (RBPs). One of the major roles of phase separation is to generate condensates, membrane-less organelles including stress granule, Cajal body, and nucleolus.

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